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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59060187f308b07453ef937d2c93bd08c4acbebfb1dfe8f55a8436a5616e03c2' 
  AND token = '14w3XuQdplfsX0HKw6NQP3zGu32XfT8Ha5dMwT+4BeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}