SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '848d47ad4bf5cc5fc312cd915d14b6cbf73f0c6517a47b88a18a168f45d4196c' 
  AND token = 'F4yYp3wQXpzRVUntKKQfqi+RcAf7ASgXWZsFaEQEaZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}