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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c4a350e14f555d68f9a2207b05cdc76afbca2de52972364448365abfbff99dc' 
  AND token = 'toGi23qKI+as7PQ6aofEszDQZzOFAkRhZ9ELR5p2JGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}