SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cb26d7950e5f59d5ea8c556122bedfd032ada705b30f9f695773c23d9105c9f' 
  AND token = 'GIIeJZtc/H5DZWwEH38XVWreguI/bXw3TtLkWugHt5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}