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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '861ec801d3f289348b80993c50280460b9ebf683f9539133fb5bb4fc7e0a31c7' 
  AND token = 'NrrA4qgesrixy+Mn6t04X0vhnOa5hul8/vecvBwfjaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}