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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '572865da7edd05de6e2cde1e2025f8c021ace1174fec50c7a42ef9fba79a2b8c' 
  AND token = 'vLXMLT30pkLmawkLFjGL9c8+reBLejkB+W08eL0R5kY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}