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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1e29622993760e64abf7610f9378c0e8b29419d7fa1d134d016d829a5c19a8b' 
  AND token = '1XVPI7BiJVndmsiaEMmqI131nSNQXQO9VlNCvk4aIIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}