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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16105dce42e613ba65045b94b443ecfe157c01a0c5f5c725d5a10a007b6e8757' 
  AND token = 'Sq6Hk9FPPKFo7s5ZkAWDHEaXbFkNY9XTWa/wxPhc3EE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}