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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a72732bfaf8ce9a84f0eda241cd996df69cd0ff6c89415e246f98a7a489aec1' 
  AND token = 'spvpV3Sx3MJCXaLUSRMkI+wzS/1I5hUr9WYh4oFMQn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}