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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54234d0761ba60718bf1eaf2f2f487a7bec1e19aa0a3291d54d4e8aa4ad1eb2f' 
  AND token = '/DdtGRaAWMbHUyY4A0mce7UgZD5XpnGIcOE7D7/SFb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}