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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '437f6784471982a3ad2e17d772ef981ad69b55863c417e49968b39b489486b4e' 
  AND token = '8FmzsKEjVJ3y/wWNhy1pEWIbco+kwO9dzFi4isyczpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}