SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3129225edb86e05bb554d0065e7b8d4cda4b17ff1ec214de358baf90f1bbf7e' 
  AND token = 'vJgAoKH4SZvFh6JTE4cZKTmd5xWiHQIxIBnFVLENwbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}