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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5694326260c31d4fbef62bdc0295d0f01e230780e18c1aa150036de910370281' 
  AND token = 'gUSNBUIL+EGKrJEpTKUqNcK5ULhrH/MZn9x2k3+RPPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}