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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4890965fa1c535a25d851fc5891e4ae3c79760fae9f2a6999359e9432e4fb8c5' 
  AND token = '8MVaZqOwxSdHY6A35xDTjtR1z2nntgdJ7wyXcN2G+g4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}