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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a03dd4239bb0992b85682e21e6a268c48c4c646d7305b1611f704c3144d4332b' 
  AND token = 'OSk9AMS5+CpBP9Ygx3wwb1XhCBO1DOyZT4KKDUed3JA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}