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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26e4d4ed1029f534c8b21fb785d7a46a898a3a6f23221bc7f0592a18f844a8b4' 
  AND token = 'oXQ0i4s0omU5SQlBaEDxw4CmRI2nyY2xu8khOS9QGO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}