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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11a27d9305d7bb0b87ce2d6009955ecc8f1ff2fe99d2e59b03b3af40eb3d7224' 
  AND token = 'fp03aQ0UtfF84rWIDFpxmdVGqYZMdIj2DRek+CuSbWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}