SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb165228182f62f6ee4baea34b965c56177b9befbd7fa4eb920365584f9cb042' 
  AND token = '3X9wTZKzNiXpLQj0J5mjOXJ02W4ZeR98WA2gIGUH3CQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}