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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de10bd629c34aa2d7916b93ef77c99d2b8f366f93d24f95d6e7e8f7f7130c857' 
  AND token = 'H6FiDEVS3J8cVC5tGvHxIk6SzhevvqJ20fX0TjZX77I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}