SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '752b5dccebad2c42caef5f244423ab494e90f7dd74b3e545898e3662ac76f514' 
  AND token = 'm9q3xMEwvX8y7xm+1+H1jvFbcaO8jlFbIqva1Pz8tHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}