SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a6b4342c66240056161c4e96493cff2d509c0273f9cd60d585b03ba67c69b1a' 
  AND token = '+TTpFkFYfhgG2Mk5qqtd3fvQObHanvBSbARm1LnSIRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}