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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13a673e4dd7dc84f4b3d0ffb26e704a8e945346a6115073f9cd7f4e6fead8c38' 
  AND token = '6D/dPKe/DCE/ekRVRciCdvE+RBrpvPz623CyUDPw8tA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}