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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71eba08e3d416985209ea291f952df9f44429de4f78ffb61da3718a6b3100752' 
  AND token = 'ni8qVYWR5Hh03nf0Bd3iIoRonXwFmWJBGVewL9m42HI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}