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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e8d4565df1ee9740f1db3585159054dc4d87340fc55fe95c45dc08ce4d475f9' 
  AND token = 'zuGCsTzzXex0BbHlnR9wp4m9SiNcKTcyjjZQVFMz+/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}