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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80de4f0cff0ae6d795f86f22340344c10e96e29d7a2ab173c3e614c78aa2f798' 
  AND token = '4BPFatXge/VSDPN/2BptvSg9O29wqN07Yn9+1h2gMII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}