SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfa91cb5b2ef09d549a5221ae69b05cad57300c2f9bbaa064fd1ad96f8985310' 
  AND token = '2a6TDuG/F3DV1ZTBFgiBYxQR5cLT1OtYK6klJpZnaJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}