SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa1363ea8683d08353b31bb4bf634f7409a82fb6f11f6244986108acf14bcda6' 
  AND token = 'AT6kH8XhI+FCAIEk6j6HTGAkEzTmSip+KXtU5Ek7tzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}