SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe5ad90b296dec6bf344a48510b2ee843d623a54840322953b1d63d44c64aedd' 
  AND token = 'l6QR2rg++w4FqAeqGKhFVkApvlP233JmoEYmxFv0fvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}