SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4081382d2b9c245c94860696bd479a763d9bb2c7b79558e756ac01819c91ab2d' 
  AND token = '45vk2nKlVkucz8zmJK0nHvDfIB2MyAaYWNyOmOohmPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}