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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acf66b4a38e157a3f99d8346f14bfcdbaadc31082e1cd37128cd78284dc8d3c5' 
  AND token = 'gyIs5MN4+afOfQNI3O+7hT9U2YfDHFNaauJv9v75aTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}