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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3532761825fd76267791d2db30802056f8ba3f5ee9828fa621a87a246d85d09f' 
  AND token = 'Gu+5UU++uUEX5B8JWAesaxo5fjAl3mnPVRah0DdfUfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}