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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c0b1732a8f6c6336dc57fe11aacf64a6ebe81bb551968149180b02a32fa75ef' 
  AND token = 'bzZO/UhrI8MWc2SJbe5vH/n16zJ+XRM/QFKVklLlPzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}