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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12ca4b832d1aee4fce70d84164d79dae3f9e5524361c4f09c3f6a82fc4c407b9' 
  AND token = 'u5AaO2lTZuwxt65KzPwsjuwayE93qPBouU6aF4W5/JU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}