SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c53aa58ebb54cb2083d19ff16bd5ebdc683b409f683070af418dc624a40e76be' 
  AND token = 'BdGOOWC+Fsm+6m/3G4JGQ9CWm+XFG57HUl4JViDHuVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}