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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3b268fab4d0a99641a47dc4a4ca7530ac3782c92bcb26c7339767beb6b5729b' 
  AND token = 'nTN2xXWA5yVrPSxUihLKh3UGd+NG8TxSOLM1RGoehFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}