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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '583ac709e55d7b014389d952d11b73ba0608aa97d4de02a2e530fd33a5b6aaa4' 
  AND token = '1oqfaEuENkrCGFsOL6PHhelDd+B5gHiIr+D/JLKG1bQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}