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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e9ee735c795c4d1d9e0b7f1ad844dca5980b1df52f1324ebda4f6cd023aea7a' 
  AND token = 'b0JEc0kxjUu05U2pMjo2OmYyovQnZ+FEkFEMnBs4oF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}