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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b801bd05ebe5418b3d71656b85132ca71af2b6d84a0a799550a41860879a5464' 
  AND token = 'gJ82sMRe+qbx6PQH1TgnYAnH6MgTVnUoDPuJj49RTcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}