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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44c4b4a8032d2fd2505eb51daf3f29f48a2be6ba02aeb3dd41e37fa3311c5954' 
  AND token = 'tZmwTdMurDgR8xysl3LFD03Qc01PrEkpYAP93LjPduw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}