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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5cfdc5b202b2bbab221f8115bac4bd6154cf2a35d49956c0ae56430bc7bb284' 
  AND token = 'Y8P5PSkUKeFLLPu4UbYQOpRdcyA27qA/WMNZzuC2dmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}