SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '256fd0d11c01247da065000ba254040986c7a7dfc16283ae1bdef7caaa117892' 
  AND token = 'JnMBV3h4ses4YpOuyfAblVCcUst7YYkX5vfCQ73cnzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}