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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b53e9531d9101057991e867d2a075c4a99d4ccc0195e71212420390522461b37' 
  AND token = 'b3hdFx7Pe2Bzm6k0ULzWQ4oP02bCz5BvOkob71X/SgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}