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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0eefa56234cce2f998e72f1c2622b25d22df602940f0701e373d6cf9574b6cb3' 
  AND token = 'XLF5+RoS8l/CKIctvA3VcOeXUUys7gynPIZ+vTLkMzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}