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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e10b5cff0d3899d18d562b499d15f2b5495be7dcf4182445a3f961c41a4bd065' 
  AND token = 'Bt1i1OcVfrZmJf/OPeD6R2/+DdO7637ST6owGvyeLKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}