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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed464efdc1632bf609b5adba93c64e36dc8621bc73f0c64099ce14fcd3a43293' 
  AND token = 'XI0tw/msW3wlS7e3zoNfRYJgGe7/cH0M1nFSvVSfmmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}