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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe4e299e15d38e6f52310517c8cbe727b6f9b8209d4f7990664d42f89f45bda8' 
  AND token = '61ltN3+mouPVpelhEXMcW3tPu5OFDJlydXiMmEMGreE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}