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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '253f2e0c8c2b693095513d923c6613f658a2755c3b2c482f3c4842661face9e8' 
  AND token = 'KpfLKRhkAUF30knEBzbk8qROEk+QTBmXMY6NcE6YYfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}