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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59763ee8125e5a990cba67ec7eb50d58eb836de51167d565e4670bb0ad9f1267' 
  AND token = '44bJEV3G8qiXsqUu3r/kdNnP1j2O1gRcGzteknpUFIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}