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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c10473ad04b6f9ed1a2b60e635084114ad240d14093fb0d9500dedc85d8ac60' 
  AND token = 'WqT1X+/Bm4J/yrwapPe0zmV34Y7W3e2lUCgSFtheQV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}