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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '503c72cf54128367a628196b84b9fad1cc42cec1f965b2cc6dc3e48d51551859' 
  AND token = 'Qy5hFC6/qvG1f/mM+MNFchzF2Zv6gyAjk4Zeok/iXas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}